Guitar Amplifier

For high power bass amps, consider the ICEpower300AS1, delivering 300W complete with universal power supply and aux supplies for the pre-amp. Alternatively, for a classic bass design amp see Exicon lateral MOSFETs.
The SPN1001-FV1 single chip digital reverb will add the essential effects with minimum hassle. The SAM5504 adds reverb, distortion effects plus USB interfaces to play along or record, as well as a processor for all the control knobs and indicators.
The THAT4305 Analog Engine will add a great sounding compressor to any amplifier.
Recommended parts:

Single Channel AF Power Amp Pentawatt
- High output power (50W Music Power IEC 268.3 Rules)
- High operating supply voltage (50V)
- Single or split supply operations
- Very low distortion

Spin FV-1 Digital Multi-Effects IC
- Integrated stereo ADC and DAC
- 8 internal programs + 8 external programs
- Easy customization with external EEPROM
- 3 potentiometer inputs for real-time parameter adjustment

Power Darlington 160V 15A
- In-built Temperature Sensor
- Complementary Type to STD03P
- Built-in temperature compensation diodes
- High power (160 W) handling in a small package (TO-3P), for minimized heat sink requirements

JFET Input Dual Op Amp
- High Quality Audio
- J-FET Input
- Low Noise 13nV/√Hz typ.
- Low Distortion 0.003% typ.(Av=10)

Low-cost Effects Processor and Keyboard Synthesizer
- Up to 81 voice Polyphony (with effects)
- Dream DSP Array of 4 new 24bit/56bit DSP cores (P24XT) supporting 56bit MAC operations (200M MAC/sec)
- New speed optimized 16bit CPU (P16XT) running at 200MHz
- Built-in 1kbit eFuse for configuration and security (program code and sound bank protection)

300W Amplifier with Power Supply
- 300W at 1% THD+N, 4Ohm
- 260W at 0.1% THD+N, 4Ohm
- 380W at 10% THD+N, 4Ohm
- 450W at 1% THD+N, 2.7Ohm

Audio Effects DSP
- 16 core registers
- 128 x 32-bit RAM based registers
- 4 digital SIN LFOs, 2 Ramp LFOs
- Built in FLASH for 16 programs

'Analog Engine' Dynamics Processor
- Pre-trimmed VCA and RMS-level detector
- Wide supply voltage range: ±4.5V to ±16V
- Low supply current: 3.5 mA typ. (±15V)
- Wide dynamic range: 117 dB (VCA),60 dB (RMS-level detector)